Tumor resistance is promoted by anti-cancer protein

Lack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the tissue, the body has innate mechanisms that "kick in" to make the cells of the hypoxic tissue more resistant and assist in tissue repair. One such mechanism is the expression of a protein called Hypoxia Induction Factor (HIF), which controls several processes such as glucose uptake, growth of blood vessels and cell proliferation. Despite its beneficial role in some diseases, HIF has also been found to be an important contributor towards cancer progression.