Breaking the 'stalemate' in the most common soft tissue sarcoma in children

A phase 2 clinical trial has found that combining a molecular targeted drug called temsirolimus with chemotherapy shows promise in the treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in childhood. The Children's Oncology Group trial was led by Leo Mascarenhas, MD, MS, Deputy Director of the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles. Results were recently published online in the Journal of Clinical Oncology.